中文 
Recombinant Human FGF-10(Cat. No.:CR11)
基本售价：14400.00元
Recombinant Human FGF-10(Cat. No.:CR11) 该产品共有2篇文献引用 产品描述Recombinant Human Fibroblast Growth Factor 10 is produced by our E.coli expression system and the target gene encoding Gln38-Ser208 is expressed.蛋白编号O15520 产品别称Fibroblast growth factor 10;FGF-10;Keratinocyte growth factor 2;FGF10;KGF-2;KGF2分子量19.5 KDa表观分子量19-22 KDa, reducing conditions剂型描述Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, pH 8.0.内毒素Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.纯度-SDS-PAGEGreater than 95% as determined by reducing SDS-PAGE. 纯度-SEC-HPLCGreater than 95% as determined by SEC-HPLC. (Regularly tested) 生物活性-Cell Based AssayMouse Gastric organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) , R-spondin 1 (Cat#CX83) and FGF-10 (Cat#CR11). The organoids showed good morphology. Mouse bile duct organoids were cultured with EGF (Cat#C029) , R-spondin 1 (Cat#CX83) ,FGF-10 (Cat#CR11) and HGF (Cat#CJ72). The organoids showed good morphology. 复溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.运输条件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.产品背景Fibroblast growth factor 10 (FGF-10, KGF-2), is a member of the fibroblast growth factor (FGF) family that includes FGF-3, -7, and -22. KGF-2 is secreted by mesenchymal cells and associates with extracellular FGF-BP. It preferentially binds and activates epithelial cell FGFR2 and interacts more weakly with FGFR1. It plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. It exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 is required for normal branching morphogenesis. Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG). ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.仅供科研或生产使用，不可直接应用于人体。
Recombinant Human RSPO1 (C-6His)(Cat. No.:CX83)
基本售价：17600.00元
Recombinant Human RSPO1 (C-6His)(Cat. No.:CX83) 该产品共有5篇文献引用 产品描述Recombinant Human R-spondin-1 is produced by our Mammalian expression system and the target gene encoding Ser21-Ala263 is expressed with a 6His tag at the C-terminus.蛋白编号Q2MKA7 产品别称RSPO1; R-spondin1; RP11-566C13.1; CRISTIN3; FLJ40906; RSPO Rspo1; R-spondin; Rspondin; RP23-325M14.2; Roof plate-specific spondin-1分子量27.8 KDa表观分子量40 KDa, reducing conditions剂型描述Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.内毒素Less than 0.01 EU/µg as determined by LAL test.纯度-SDS-PAGEGreater than 95% as determined by reducing SDS-PAGE. 生物活性-Cell Based AssayMeasured by its ability to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 4.06 ng/ml. Mouse intestinal organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) and R-spondin 1 (Cat#CX83). After five days of culture, the organoids showed good morphology and germination rate. Mouse Colon organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) , and R-spondin 1 (Cat#CX83). The organoids showed good morphology. Mouse Gastric organoids were cultured with EGF (Cat#C029), Wnt3a (Cat#C22R), Noggin (Cat#C028) , R-spondin 1 (Cat#CX83) and FGF-10 (Cat#CR11). The organoids showed good morphology. Mouse bile duct organoids were cultured with EGF (Cat#C029) , R-spondin 1 (Cat#CX83) ,FGF-10 (Cat#CR11) and HGF (Cat#CJ72). The organoids showed good morphology. Human intestinal organoids (ipsc source) were cultured with Activin A(Cat#C687) , BMP-4(sample) , EGF (Cat#C029) , Wnt3a (Cat#C22R), Noggin (Cat#C028), R-spondin 1 (Cat#CX83) and FGF-4 (Cat#CR08) . The organoids showed good morphology. Human endometrial epithelial organoids were cultured with EGF (Cat#CH28) and R-spondin 1 (Cat#CX83). The organoids showed good morphology. Data were kindly provided by Novoprotein's customer. Thanks for her contribution. 复溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.运输条件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.产品背景RSPO1 is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. RSPO1 is required for the early development of gonads, regardless of sex. It has been found in mice only eleven days after fertilization. To induce cell proliferation, it acts synergistically with WNT4. They help stabilize β catenin, which activates downstream targets. RSPO1 is necessary in female sex development. It augments the WNT/β catenin pathway to oppose male sex development. In critical gonadal stages, between six and nine weeks after fertilization, the ovaries upregulate it while the testes downregulate it. RSPO1 can potentially aid in the treatment of mucositis, which is characterized by inflammation of the oral cavity. This unfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and neck tumors.仅供科研或生产使用，不可直接应用于人体。
Recombinant Human KGF(Cat. No.:CH73)
基本售价：19200.00元
Recombinant Human KGF(Cat. No.:CH73) 该产品共有1篇文献引用 产品描述Recombinant Human Fibroblast Growth Factor 7/Keratinocyte Growth Factor is produced by our E.coli expression system and the target gene encoding Cys32-Thr194 is expressed.蛋白编号P21781 产品别称Fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF分子量18.9 KDa表观分子量17 KDa, reducing conditions剂型描述Lyophilized from a 0.2 μm filtered solution of 20mM Tris，1mM EDTA，5% Trehalose, 0.02% Tween 80, pH 8.0.内毒素Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.纯度-SDS-PAGEGreater than 95% as determined by reducing SDS-PAGE. (QC verified) 纯度-SEC-HPLCGreater than 95% as determined by SEC-HPLC. (Regularly tested) 复溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.运输条件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.产品背景Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.仅供科研或生产使用，不可直接应用于人体。
Recombinant Human PECAM-1 (C-6His)(Cat. No.:CS74)
基本售价：400.00元
Recombinant Human PECAM-1 (C-6His)(Cat. No.:CS74) 产品描述Recombinant Human Platelet Endothelial Cell Adhesion Molecule is produced by our Mammalian expression system and the target gene encoding Gln28Lys601 is expressed with a 6His tag at the C-terminus.蛋白编号AAH51822.1 产品别称Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1分子量65.3 KDa表观分子量75-110 KDa, reducing conditions剂型描述Lyophilized from a 0.2 μm filtered solution of PBS, 1mM EDTA, pH 7.4.内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.复溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.运输条件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.产品背景Platelet Endothelial Cell Adhesion Molecule (PECAM1, CD31), is a heavily glycosylated transmembrane protein belonging to the immunoglobulin (Ig) superfamily of cell adhesion molecules. CD31 is composed of an extracellular domain (ECD) of 574 amino acids (aa) containing six Ig-like domains, a transmembrane domain, and a 118 aa cytoplasmic domain. CD31 is highly expressed on endothelial cells and at a lower level on platelets, granulocytes, macrophages, dendritic cells, T and B cells, and natural killer (NK) cells. It is involved in cell adhesion and is required for transepithelial migration of leukocytes (TEM). CD31 acts as a homophilic receptor through its extracellular domain and is involved in downstream signaling via its cytoplasmic domain. This domain contains highly conserved ITIM motifs which, once tyrosine phosphorylated, recruit and activate the signaling molecules Src and SHP2. The resulting inhibition of TCR signaling increases the activation threshold of T cells, thus reinforcing peripheral tolerance and preventing development of autoimmunity. CD31 additionally regulates immune responses by acting as a key inhibitory receptor in dendritic cell development. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells.仅供科研或生产使用，不可直接应用于人体。
Recombinant Mouse IL-4 (C-6His)(Cat. No.:CK74)
基本售价：17600.00元
Recombinant Mouse IL-4 (C-6His)(Cat. No.:CK74) 该产品共有24篇文献引用 产品描述Recombinant Mouse Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His21-Ser140 is expressed with a 6His tag at the C-terminus.蛋白编号P07750 产品别称Interleukin-4; IL-4; IL4; B-cell IgG differentiation factor; B-cell growth factor 1; B-cell stimulatory factor 1; BSF-1; IGG1 induction factor; Lymphocyte stimulatory factor 1分子量14.6 KDa表观分子量15-19 KDa, reducing conditions剂型描述Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.复溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.运输条件The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.产品背景Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.仅供科研或生产使用，不可直接应用于人体。
NovoStart SYBR qPCR SuperMix Plus试剂
基本售价：1280.00元
NovoStart SYBR qPCR SuperMix Plus试剂 该产品共有552篇文献引用 产品描述本制品是采用SYBR Green I嵌合荧光法进行Real Time PCR的专用试剂。预混液中已经将DNA聚合酶、精心优化的反应Buffer、dNTPs、SYBR Green I等试剂预混在一起，是一种2×浓度的预混型试剂，进行实验时，PCR反应液的配制十分简单方便。本制品使用新型抗体修饰的HotStart Taq DNA聚合酶，并结合精心优化的反应Buffer，从而有效抑制低温下的非特异性扩增，提高反应特异性和扩增效率，能够在更宽广的范围内进行准确定量。产品特点高特异性：采用新型工艺制备抗体修饰的HotStart Taq DNA聚合酶，无需热启动即可进行PCR反应，大大提高PCR扩增的特异性。高效：Novoprotein精心配制的RealTime PCR专用2×SuperMix，具有更高的扩增效率和扩增灵敏度。快捷：PCR反应所必需试剂集于一管之中，数分钟即可完成反应体系配制。保存条件-20℃避光储存。如需在一段时间内经常取用，可在2~8℃条件下储存3个月。避免反复多次冻融。质量控制纯度检测：所有组分经检测均无核酸内切酶残留、核酸外切酶残留、核酸残留。使用建议使用：请上下颠倒轻轻混合均匀，避免起泡，并经轻微离心后使用。反应液的配制、分装请使用新的（无污染的）枪头、Microtube等，避免污染。建议反应体积为20～50μl。引物设计：一般为了增加灵敏度及扩增效率且抑制非特异性反应，扩增目标序列越短越好。建议设计成200bp以下。仅供科研或生产使用，不可直接应用于人体。
Recombinant Mouse TNF alpha
基本售价：2520.00元
Recombinant Mouse TNF alpha 产品描述Recombinant Mouse Tumor Necrosis Factor Alpha is produced by our E.coli expression system and the target gene encoding Asp89-Leu235 is expressed.蛋白编号P06804 产品别称Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Soluble Form; Tnf; Tnfa; Tnfsf2分子量16.4 KDa表观分子量14 KDa, reducing conditions剂型描述Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.内毒素Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.纯度-SDS-PAGE
RNase R
基本售价：2000.00元
RNase R 产品描述核糖核酸酶R (Ribonuclease R，RNase R) 来源于大肠杆菌RNR超家族，是一种镁离子依赖性的3'—5'核糖核酸外切酶，可从3'—5'方向将RNA逐步切割成二核苷酸和三核苷酸。RNase R几乎能够消化所有线性的RNA，但不易消化环状RNA、套索结构RNA和3'端突出少于7个核苷酸的短双链RNA分子。 RNase R常用于基因表达和可变剪切研究，可消化线性RNA以富集环状RNA或套索结构RNA。保存条件-20±5℃仅供科研或生产使用，不可直接应用于人体。
Lysis dilution buffer（150 mM NaCl/5 mM EDTA）500ml
基本售价：170.00元
Lysis dilution buffer（150 mM NaCl/5 mM EDTA）500ml
TripleSelect无动物源常温胰酶
基本售价：260.00元
TripleSelect无动物源常温胰酶 【保存条件】 室温保存12个月, 2–8°C或–20°C保存24个月【概述】 TripleSelect与胰蛋白酶一样，可裂解赖氨酸和精氨酸C-末端上的肽键。但是，TripleSelect无与伦比的纯度提高了特异性，其原因在于只有一种酶发挥作用。这减少了胰蛋白酶和其他提取物中存在的多种酶的裂解作用造成的损害。【产品特点】 对细胞作用温和：纯度提高了特异性，其原因在于只有一种酶发挥作用。这减少了胰蛋白酶和其他提取物中由于多种酶切割造成的损害。在室温下保持稳定：在室温或4°C下可保持稳定12-24个月，因此易于储存和处理、方便快捷。无动物来源蛋白：与常用猪胰蛋白酶不同，本试剂不含动物来源成分。无需终止，易于使用：无需使用胰蛋白酶抑制剂（如FBS）终止消化，PBS或DMEM等稀释后自动失活。【使用建议】 1.使用前将TripleSelect和完整的生长培养基恢复至室温。2.将待消化细胞培养器皿中培养去除。3.使用DPBS（无钙镁）清洗细胞，清洗完去除DPBS液体。4.加入相应体积的TripleSelect消化液（如25cm2瓶中加入1-2ml TripleSelect消化液，75cm2瓶中加入5ml TripleSelect消化液）5.37°C孵育至细胞变圆脱落（镜下观察），可轻拍培养瓶/皿。6.加入5ml完全培养基至培养瓶/皿（体积根据不同面积培养瓶/皿），可轻轻吹打使细胞更好分离。7.将含细胞的液体移入15ml无菌离心管中。以200-500g转速离心5-10分钟使细胞沉淀。8.去除上清后，加入含血清的完全培养液使细胞沉淀重新悬浮，即可用于后续实验【注意事项】 1. 注意无菌操作，尽量避免污染。2. 为了您的安全和健康，请穿实验服并戴一次性手套操作。
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