中文 
D(+)-Trehalose dihydrate；D-海藻糖二水
基本售价：600.00元
D(+)-Trehalose dihydrate；D-海藻糖二水产品简介CAS6138-23-4中文名称D-海藻糖二水英文名称D(+)-Trehalose dihydrate别名α,α-Trehalosedihydrate纯度HPLC≥98%单位瓶分子式C12H22O11·2H2O分子量378.33外观（性状）White to off-white Solid储存条件Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months溶解性Soluble in WaterECEINECS 202-739-6MDLMFCD00071594SMILESO[C@H]1[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@@H]1O.[2 H2O]描述D-(+)-Trehalose dihydrate可作赋形剂。(D-(+)-Trehalose dihydrate can be used as excipient.)靶点Others通路Others生物活性D-(+)-Trehalose dihydrate可用作食品成分和药物赋形剂。[1]In Vitro海藻糖二水合物是一种安全的，天然存在的二糖，用作食品成分和药物赋形剂[1]。数据来源文献[1]. Megarry AJ, et al. Amorphous trehalose dihydrate by cryogenic milling. Carbohydr Res. 2011 Jun 1;346(8):1061-4.规格20mg 10mM*1mL in Water 100mgD-(+)-Trehalose dihydrate可作赋形剂。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.D(+)-Trehalose dihydrate；D-海藻糖二水_助溶剂&增溶剂_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
D-Sorbitol D-山梨醇
基本售价：700.00元
D-Sorbitol D-山梨醇产品简介CAS50-70-4中文名称D-山梨醇英文名称D-Sorbitol别名D-山梨糖醇单位瓶纯度HPLC≥98%分子式C6H14O6 分子量182.17外观（性状）White to off-white Solid储存条件Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months溶解性Soluble in Water/DMSOMDLMFCD00004708ECEINECS 200-061-5InChIKeyFBPFZTCFMRRESA-JGWLITMVSA-NInChIInChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1PubChem CID5780SMILESOC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O描述是蔷薇科植物的主要光合作用产物,是一种具有保湿功能的特殊甜味剂,可作为湿润剂、螯合剂和稳定剂。(It is the main photosynthesis product of Rosaceae, a special sweetener with moisturizing function, and can be used as wetting agent, chelating agent and stabilizer.)靶点Endogenous Metabolite通路Others规格100mg 10mM*1mL (in Water) 10mM*1mL（in DMSO） 200mg是蔷薇科植物的主要光合作用产物，是一种具有保湿功能的特殊甜味剂，可作为湿润剂、螯合剂和稳定剂。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.D-Sorbitol D-山梨醇_抑制剂＆拮抗剂＆激动剂_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
Hygromycin B 潮霉素B 索莱宝
基本售价：700.00元
Hygromycin B 潮霉素B产品简介CAS31282-04-9中文名称潮霉素B英文名称Hygromycin B别名Destomycin A; Hygrovetin单位瓶纯度≥90%分子式C20H37N3O13分子量527.52外观（性状）Off-white to yellow Solid储存条件Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months溶解性Soluble in Water ≥100mg/mLMDLMFCD00036846ECEINECS 250-545-5InChIKeyGRRNUXAQVGOGFE-XKIAHZFYSA-NInChIInChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6-,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20+/m1/s1PubChem CID23777801SMILESO[C@H]([C@H]1O)C2(O[C@@]([C@@H](N)CO)([H])[C@@H]1O)O[C@@]([C@@H](O[C@@H]3CO)O[C@@]([C@H]([C@H](N)C4)O)([H])[C@@H]([C@H]4NC)O)([H])[C@@]([C@H]3O)([H])O2描述是抑制原核和真核细胞的氨基糖苷类抗生素,通过干扰移位、促进70S核糖体的误译来抑制蛋白质合成。(It is an aminoglycoside antibiotic that inhibits prokaryotic and eukaryotic cells, inhibiting protein synthesis by interfering with translocation and promoting mistranslation of 70S ribosomes.)靶点Bacterial;Fungal通路Anti-infection生物活性Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.[1-3]In VitroHygromycin B, an aminocyclitol antibiotic that strongly inhibits both 70S and 80S ribosomes, is synthesized by Streptomyces hygroscopicus[1]. Hygromycin B at 0.38 mM concentration completely halts yeast cell growth in rich media, presumably by preventing protein synthesis by cytoplasmic ribosomes. Polypeptide synthesis in cell-free extracts from rabbit reticulocytes, wheat germ and yeast is strongly blocked by low concentrations ofhygromycin B. The antibiotic inhibits peptide chain elongation by yeast polysomes by preventing elongation factor EF-2-dependent translocation. The inhibition of translocation by hygromycin B might result from the stabilization of peptidyl-tRNA bound to the ribosomal acceptor site[2].In VivoHygromycin B inhibits protein synthesis by blocking ribosomal translocation without causing significant misreading in vivo[3]. Constitutive expression of the bacterial hygR gene in transgenic mice in vivo confers resistance to hygromycin B[4].动物实验Hygromycin B is dissolved in sterile water. The mice C57BL/6J-TgN(pPWL512hyg)1Ems carrying hygR are treated with a single dose of hygromycin B i.p. at doses that starts at 2.7 mg/kg and increases by 50% for each consecutive dose. Control wild-type C57BL/6J mice are treated with the same volume of sterile saline. Total volume injected is 0.5 mL. The health status and body weights of animals are monitored daily for 10 consecutive days[4].数据来源文献[1]. Pardo JM, et al. Biochemical basis of resistance to hygromycin B in Streptomyces hygroscopicus--the producing organism. J Gen Microbiol. 1985 Jun;131(6):1289-98.[2]. González A, et al. Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. Biochim Biophys Acta. 1978 Dec 21;521(2):459-69.[3]. Pfister P, et al. Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B. Antimicrob Agents Chemother. 2003 May;47(5):1496-502.规格200mg 10mM*1mL (in Water) 1g备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.
Posaconazole；泊沙康唑
基本售价：840.00元
Posaconazole；泊沙康唑产品简介CAS171228-49-2中文名称泊沙康唑英文名称Posaconazole别名Pcz;Noxafil;Stereoisomer;Posconazole纯度HPLC≥98%单位支分子式C37H42F2N8O4分子量700.78外观（性状）White to off-white Solid储存条件Powder : -20℃, 2 years;In solvent(母液): -20℃, 1 month; -80℃, 6 months溶解性Soluble in DMSOECEINECS 200-659-6MDLMFCD00941162SMILESFC1=CC=C([C@@]2(CN3C=NC=N3)C[C@H](COC4=CC=C(N5CCN(C6=CC=C(N7C=NN([C@@H](CC)[C@H](C)O)C7=O)C=C6)CC5)C=C4)CO2)C(F)=C1描述Posaconazole 是一种广谱的,二代三唑类物质,具有抗真菌活性。(Posaconazole is a broad-spectrum, second-generation triazole with antifungal activity.)靶点Fungal通路Anti-infection生物活性Posaconazole 是一种广谱的，二代三唑类物质，具有抗真菌作用。[1-5]In VitroPosaconazole对念珠菌和曲霉菌的分离株具有活性。表现出对氟康唑，伏立康唑和两性霉素B的抗性，并且比其他三唑对抗接合菌的活性要高得多[2]。Posaconazole具有有效的杀螨活性。胺碘酮与Posaconazole协同作用。 Posaconazole也会影响和破坏T. cruzi中的Ca2 +稳态。Posaconazole阻断麦角甾醇的生物合成，麦角甾醇是寄生虫存活的必要条件。Posaconazole对epimastigote（细胞外）阶段的增殖具有明显的剂量依赖性作用，最小抑制浓度为20 nM，IC50为14 nM。针对临床相关的细胞内无鞭毛体形式的寄生虫，Posaconazole甚至更有效。Posaconazole的抑制浓度最低，IC50值分别为3 nM和0.25 nM [1]。In Vivo单独使用胺碘酮治疗感染动物可减少寄生虫血症，提高60天存活率（未治疗对照组为0％，胺碘酮治疗组为40％），与Posaconazole联合使用可延缓寄生虫血症的发生[1]。与在禁食状态下单独使用Posaconazole相比，Posaconazole和Boost Plus的共同给药增加了药物暴露。食物，尤其是脂肪含量高的膳食，可显著提高Posaconazole的生物利用度。当与高脂肪和无脂肪餐一起食用时，全身暴露于Posaconazole分别增加4倍和2.6倍[3]。Posaconazole和胺碘酮可构成有效的抗T。 cruzi疗法副作用小[4]。每日两次剂量≥15mg/ kg体重，Posaconazole可延长小鼠的存活时间并减轻组织负担[5]。细胞实验寄生虫的epimastigote形式在肝输注胰蛋白胨培养基中培养，其中补充有10％新出生的小牛血清，在28℃下进行强烈（120rpm）搅拌。培养物以2×106 epimastigotes mL-1的细胞密度开始，并且以0.5-1.0×107 epimastigotes mL-1的细胞密度添加药物。通过使用电子粒子计数器以及通过血细胞计数器直接计数来测量细胞密度。细胞活力随后是台盼蓝排除，使用光学显微镜检查。如前所述，无鞭毛体在Vero细胞中培养，所述Vero细胞维持在补充有1％胎牛血清的最小必需培养基中，在37℃下在潮湿气氛（95％空气-5％CO 2）中。每个细胞用10个组织培养物衍生的trypomastigotes感染细胞2小时，然后用磷酸盐缓冲盐水（PBS）洗涤三次以除去非粘附寄生虫。添加含有和不含药物的新鲜培养基，将细胞培养96小时，培养基更换为48小时。使用光学显微镜直接测定感染细胞的百分比和每个细胞的寄生虫数量，并如前所述进行结果的统计分析。使用GraFit程序通过非线性回归计算IC 50值。对照和药物处理的细胞外epimastigotes中的细胞质游离Ca 2+浓度通过荧光测定法使用Fura-2测定，再次如前所述。通过使用时间扫描共聚焦显微镜，在用克氏锥虫无鞭毛体感染的个体Vero细胞上监测亚细胞Ca 2+水平和线粒体膜电位，如其他地方详细描述的。简而言之，用T. cruzi无鞭毛体严重感染（72小时）的Vero细胞接种到22×40mm玻璃盖玻片（0.15mm厚度）上，并与10μM细胞渗透性Rhod-2和10μg/ mL罗丹明-123同时孵育。在37℃下在培养基中50分钟，然后洗涤并与含有或不含有胺碘酮的林格氏溶液一起温育。在所使用的条件下，Rhod-2的荧光主要来自细胞内富含Ca2 +的区室，如线粒体，因为其对Ca2 +的低亲和力限制了其在Vero细胞或无鞭毛体的Ca2 + - 细胞质中的荧光。罗丹明-123是一种线粒体特异性阳离子染料，严格根据其膜电位分布在线粒体内膜上。动物实验通过使用急性恰加斯病的鼠模型进行体内研究，其中雌性NMRI-IVIC小鼠（20-25g）用105或103个血流试验鞭毛体感染，并且在24小时后开始药物治疗。对于Posaconazole（30剂）和/或每隔一天50mg/kg对于胺碘酮（15剂），以20mg/kg/d连续30天给予治疗。阴性对照（即未治疗的动物）仅接受载体，而阳性对照用抗-T治疗。克唑子化合物，硝呋莫司，50mg/kg/d，30天。数据来源文献[1]. Benaim G, et al. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. J Med Chem. 2006 Feb 9;49(3):892-9.[2]. Sabatelli F, et al. In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. Antimicrob Agents Chemother. 2006 Jun;50(6):2009-15.[3]. Sansone-Parsons A, et al. Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers. Antimicrob Agents Chemother. 2006 May;50(5):1881-3.[4]. Veiga-Santos P, et al. Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi. Int J Antimicrob Agents. 2012 Jul;40(1):61-71.[5]. Sun QN, et al. In vivo activity of posaconazole against Mucor spp. in an immunosuppressed-mouse model. Antimicrob Agents Chemother. 2002 Jul;46(7):2310-2.规格5mg 10mM*1mL in DMSO 10mgPosaconazole 是一种广谱的，二代三唑类物质，具有抗真菌活性。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.Posaconazole；泊沙康唑_Anti-Fungal_Anti-infection/抗感染_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
L-Glycine；L-甘氨酸
基本售价：320.00元
L-Glycine；L-甘氨酸产品简介CAS56-40-6中文名称L-甘氨酸英文名称L-Glycine别名H-Gly-OH纯度HPLC≥98%单位瓶分子式C2H5NO2分子量75.07外观（性状）White to off-white Solid储存条件Powder : 2-8℃, 2 years; In solvent(母液): -20℃, 1 month; -80℃, 6 months溶解性Soluble in Water ≥ 6mg/mLECEINECS 200-272-2MDLMFCD00008131InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-NInChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)PubChem CID750SMILESNCC(O)=O描述是中枢神经系统的一种抑制性神经递质,同时也是glutamate的一种联合激动剂,有促进谷氨酸能NMDA (N-methyl-D-aspartic acid ) 受体兴奋的潜能。(It is an inhibitory neurotransmitter in the central nervous system and a combined agonist of glutamate, which has the potential to promote the excitation of glutamatergic NMDA (N-methyl-D-aspartic acid) receptors.)靶点Others通路Others规格500mg 1g 10mM*1mL in Water备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.L-Glycine；L-甘氨酸_氨基酸及其衍生物_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
聚乙二醇10000
基本售价：400.00元
聚乙二醇10000产品简介CAS25322-68-3中文名称聚乙二醇10000英文名称PEG10000单位瓶分子式HO(CH2CH2O)nH分子量10000外观（性状）Solid储存条件RT,2 years溶解性Soluble in WaterMDLMFCD00081839ECEINECS 203-473-3SMILES---描述聚乙二醇是一种高分子聚合物,可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。(Polyethylene glycol is a kind of high molecular polymer, which can be used in the research of drug sustained release and immobilized enzyme carrier, surface modification of medical polymer materials and so on.)靶点---规格100g聚乙二醇是一种高分子聚合物，可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.聚乙二醇10000_助溶剂&增溶剂_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
聚乙二醇800
基本售价：400.00元
聚乙二醇800产品简介CAS25322-68-3中文名称聚乙二醇800英文名称PEG800单位瓶分子式HO(CH2CH2O)nH分子量800外观（性状）White to off-white Solid储存条件RT,2 years溶解性Soluble in Water ≥100mg/mLMDLMFCD00081839ECEINECS 203-473-3SMILES---描述聚乙二醇是一种高分子聚合物,可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。(Polyethylene glycol is a kind of high molecular polymer, which can be used in the research of drug sustained release and immobilized enzyme carrier, surface modification of medical polymer materials and so on.)靶点---规格100g聚乙二醇是一种高分子聚合物，可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.聚乙二醇800_助溶剂&增溶剂_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
聚乙二醇200
基本售价：400.00元
聚乙二醇200产品简介CAS25322-68-3中文名称聚乙二醇200英文名称PEG200单位瓶分子式HO(CH2CH2O)nH分子量200外观（性状）Liquid储存条件RT,2 yearsMDLMFCD00081839ECEINECS 203-473-3SMILES---描述聚乙二醇是一种高分子聚合物,可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。(Polyethylene glycol is a kind of high molecular polymer, which can be used in the research of drug sustained release and immobilized enzyme carrier, surface modification of medical polymer materials and so on.)靶点---规格100ml聚乙二醇是一种高分子聚合物，可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.聚乙二醇200_助溶剂&增溶剂_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
聚乙二醇20000
基本售价：400.00元
聚乙二醇20000产品简介CAS25322-68-3中文名称聚乙二醇20000英文名称PEG20000单位瓶分子式HO(CH2CH2O)nH分子量20000外观（性状）White to off-white Solid储存条件RT,2 years溶解性Soluble in Water ≥100mg/mLMDLMFCD00081839ECEINECS 203-473-3SMILES---描述聚乙二醇是一种高分子聚合物,可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。(Polyethylene glycol is a kind of high molecular polymer, which can be used in the research of drug sustained release and immobilized enzyme carrier, surface modification of medical polymer materials and so on.)靶点---规格100g聚乙二醇是一种高分子聚合物，可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.聚乙二醇20000_助溶剂&增溶剂_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
聚乙二醇1500
基本售价：400.00元
聚乙二醇1500产品简介CAS25322-68-3中文名称聚乙二醇1500英文名称PEG1500单位瓶分子式HO(CH2CH2O)nH分子量1500外观（性状）Solid储存条件RT,2 years溶解性Soluble in WaterMDLMFCD00081839ECEINECS 203-473-3SMILES---描述聚乙二醇是一种高分子聚合物,可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。(Polyethylene glycol is a kind of high molecular polymer, which can be used in the research of drug sustained release and immobilized enzyme carrier, surface modification of medical polymer materials and so on.)靶点---规格100g聚乙二醇是一种高分子聚合物，可用于药物缓释和固定化酶的载体、医用高分子材料表面改性等多种方面的研究。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these methods.聚乙二醇1500_助溶剂&增溶剂_小分子化合物_索莱宝-专业生化试剂网上商城 (solarbio.com)
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